Guidelines for reporting novel mecA gene homologues.
نویسندگان
چکیده
Published Ahead of Print 6 August 2012. 10.1128/AAC.01199-12. 2012, 56(10):4997. DOI: Antimicrob. Agents Chemother. Girbe Buist and Sollid, Joseph F. John Jr., Robert Daum, Bo Soderquist Kreiswirth, Kwan Soo Ko, Hajo Grundmann, Johanna E. Boyle-Vavra, Frederic Laurent, Angela M. Kearns, Barry O'Brien, Fred C. Tenover, Duarte C. Oliveira, Susan Robert L. Skov, Kunyan Zhang, Henrik Westh, Frances David C. Coleman, Richard Goering, Philip M. Giffard, de Lencastre, Vincent Perreten, Matthew T. G. Holden, Teruyo Ito, Keiichi Hiramatsu, Alexander Tomasz, Hermínia Homologues Gene mecA Guidelines for Reporting Novel
منابع مشابه
Evidence for the evolutionary steps leading to mecA-mediated β-lactam resistance in staphylococci
The epidemiologically most important mechanism of antibiotic resistance in Staphylococcus aureus is associated with mecA-an acquired gene encoding an extra penicillin-binding protein (PBP2a) with low affinity to virtually all β-lactams. The introduction of mecA into the S. aureus chromosome has led to the emergence of methicillin-resistant S. aureus (MRSA) pandemics, responsible for high rates ...
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BACKGROUND Animals can act as a reservoir and source for the emergence of novel meticillin-resistant Staphylococcus aureus (MRSA) clones in human beings. Here, we report the discovery of a strain of S aureus (LGA251) isolated from bulk milk that was phenotypically resistant to meticillin but tested negative for the mecA gene and a preliminary investigation of the extent to which such strains ar...
متن کاملABSENCE OF mecA GENE IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ISOLATES
Methicillin-resistant Staphylococcus aureus has emerged as a serious threat to public health, causing both hospital and community-associated infections. The gold standard for MRSA detection is the amplification of the mecA gene that codes for the production of the altered penicillin-binding protein (PBP2a) responsible for classical methicillin resistance. This work determined the nature of meth...
متن کاملOrigin and molecular evolution of the determinant of methicillin resistance in staphylococci.
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most important multidrug-resistant pathogens around the world. MRSA is generated when methicillin-susceptible S. aureus (MSSA) exogenously acquires a methicillin resistance gene, mecA, carried by a mobile genetic element, staphylococcal cassette chromosome mec (SCCmec), which is speculated to be transmissible across staphylococcal...
متن کاملشناسایی ژن‌های بیماری‌زا(et A،B و tst) و مقاومت آنتی‌بیوتیکی(mecA) در سویه‌های استافیلوکوکوس اورئوس جداشده از نمونه‌های بالینی با روش Multiplex PCR
Background and Aim: Staphylococcus aureus produces many virulence factors, including toxins, immune-modulatory factors, and exoenzymes. The study was performed to determine virulence and resistance-related factors etA, etB, tst, mecA and femA in the S. aureus isolated from clinical samples using Multiplex PCR. Materials and Methods: In this cross - sectional study, a total 60 S. aureus were co...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 56 10 شماره
صفحات -
تاریخ انتشار 2012